KLHL4 protein (Gorilla gorilla) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

KLHL4

Kelch like family member 4. (718 aa)

Predicted Functional Partners:

CUL3

0.752

GRPR

0.681

SQSTM1

0.633

G3QLU7_GORGO

0.626

BBS1

0.595

BBS9

0.578

BBS4

0.563

BBS7

0.561

ENSGGOP00000041284

0.535

CPXCR1

0.518

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS1	BBS4	ENSGGOP00000012924	ENSGGOP00000003833	BBS1 domain-containing protein.	Bardet-Biedl syndrome 4.	0.999
BBS1	BBS7	ENSGGOP00000012924	ENSGGOP00000002139	BBS1 domain-containing protein.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.999
BBS1	BBS9	ENSGGOP00000012924	ENSGGOP00000048769	BBS1 domain-containing protein.	Bardet-Biedl syndrome 9.	0.999
BBS1	ENSGGOP00000041284	ENSGGOP00000012924	ENSGGOP00000041284	BBS1 domain-containing protein.	Tetratricopeptide repeat domain 8.	0.999
BBS1	KLHL4	ENSGGOP00000012924	ENSGGOP00000002271	BBS1 domain-containing protein.	Kelch like family member 4.	0.595
BBS4	BBS1	ENSGGOP00000003833	ENSGGOP00000012924	Bardet-Biedl syndrome 4.	BBS1 domain-containing protein.	0.999
BBS4	BBS7	ENSGGOP00000003833	ENSGGOP00000002139	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.999
BBS4	BBS9	ENSGGOP00000003833	ENSGGOP00000048769	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 9.	0.999
BBS4	ENSGGOP00000041284	ENSGGOP00000003833	ENSGGOP00000041284	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.997
BBS4	KLHL4	ENSGGOP00000003833	ENSGGOP00000002271	Bardet-Biedl syndrome 4.	Kelch like family member 4.	0.563
BBS7	BBS1	ENSGGOP00000002139	ENSGGOP00000012924	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	BBS1 domain-containing protein.	0.999
BBS7	BBS4	ENSGGOP00000002139	ENSGGOP00000003833	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Bardet-Biedl syndrome 4.	0.999
BBS7	BBS9	ENSGGOP00000002139	ENSGGOP00000048769	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Bardet-Biedl syndrome 9.	0.999
BBS7	ENSGGOP00000041284	ENSGGOP00000002139	ENSGGOP00000041284	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Tetratricopeptide repeat domain 8.	0.998
BBS7	KLHL4	ENSGGOP00000002139	ENSGGOP00000002271	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	Kelch like family member 4.	0.561
BBS9	BBS1	ENSGGOP00000048769	ENSGGOP00000012924	Bardet-Biedl syndrome 9.	BBS1 domain-containing protein.	0.999
BBS9	BBS4	ENSGGOP00000048769	ENSGGOP00000003833	Bardet-Biedl syndrome 9.	Bardet-Biedl syndrome 4.	0.999
BBS9	BBS7	ENSGGOP00000048769	ENSGGOP00000002139	Bardet-Biedl syndrome 9.	Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.	0.999
BBS9	ENSGGOP00000041284	ENSGGOP00000048769	ENSGGOP00000041284	Bardet-Biedl syndrome 9.	Tetratricopeptide repeat domain 8.	0.998
BBS9	KLHL4	ENSGGOP00000048769	ENSGGOP00000002271	Bardet-Biedl syndrome 9.	Kelch like family member 4.	0.578