Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCZ1BUncharacterized protein. (281 aa)    
Predicted Functional Partners:
RAB7A
RAB7A, member RAS oncogene family.
    
 0.977
MON1A
MON1 homolog A, secretory trafficking associated.
    
 0.972
MON1B
MON1 homolog B, secretory trafficking associated.
    
 0.964
RAB7B
RAB7B, member RAS oncogene family.
    
 0.947
RMC1
Regulator of MON1-CCZ1.
    
 0.822
G3SIT3_GORGO
GRIP1 associated protein 1.
    
 0.740
VPS11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
   
 
 0.724
VPS18
VPS18 core subunit of CORVET and HOPS complexes.
   
 
 0.720
VPS39
VPS39 subunit of HOPS complex.
    
 
 0.719
VPS16
Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.
    
 
 0.714
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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