STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DESDesmin; Belongs to the intermediate filament family. (470 aa)    
Predicted Functional Partners:
VIM
Vimentin; Belongs to the intermediate filament family.
  
 
 
0.956
TTN
Titin.
   
 0.901
TCAP
Titin-cap.
   
 
 0.868
SYNC
Syncoilin, intermediate filament protein; Belongs to the intermediate filament family.
    
 
 0.796
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
  
 
0.782
G3SAE6_GORGO
Plectin.
    
 0.698
NEFL
Neurofilament light; Belongs to the intermediate filament family.
   
 
0.685
MAML1
Mastermind like transcriptional coactivator 1.
    
 
 0.673
G3R317_GORGO
Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.
    
   0.644
G3RFY1_GORGO
Synemin; Belongs to the intermediate filament family.
   
 
0.577
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.