STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLA1APhospholipase A1 member A. (456 aa)    
Predicted Functional Partners:
PTDSS2
Phosphatidylserine synthase 2.
     
 0.923
PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
   
 0.922
PTDSS1
Phosphatidylserine synthase 1.
     
 0.915
MBOAT1
Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family.
    
 0.910
LPCAT3
Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family.
     
 0.906
LPCAT4
Lysophosphatidylcholine acyltransferase 4.
    
 0.903
POU2F3
POU domain protein.
    
 0.709
MAPK3
Mitogen-activated protein kinase.
    
 0.687
MAPK1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.687
LPAR3
Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family.
      
 0.570
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.