STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMCR8SMCR8-C9orf72 complex subunit. (937 aa)    
Predicted Functional Partners:
WDR41
WD repeat domain 41.
    
 0.998
G3QU07_GORGO
C9orf72-SMCR8 complex subunit.
    
 0.996
RAB39B
RAB39B, member RAS oncogene family.
    
 0.954
RAB8A
RAB8A, member RAS oncogene family.
    
 0.947
ULK1
Unc-51 like autophagy activating kinase 1.
   
 0.934
TBK1
TANK binding kinase 1.
   
 0.933
ULK2
Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
   
 0.922
TANK
TRAF family member associated NFKB activator.
     
 0.911
ARF1
ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.880
RRAGC
Ras related GTP binding C.
      
 0.811
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.