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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYMPKSymplekin. (1301 aa)    
Predicted Functional Partners:
CPSF3
Cleavage and polyadenylation specific factor 3.
   
 0.999
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.999
CPSF1
Cleavage and polyadenylation specific factor 1.
    
 0.996
WDR33
WD repeat domain 33.
    
 0.995
G3RGL8_GORGO
Cleavage and polyadenylation specific factor 4.
   
 0.995
FIP1L1
Factor interacting with PAPOLA and CPSF1.
   
 0.994
CSTF2
Cleavage stimulation factor subunit 2.
   
 0.992
SSU72
SSU72 homolog, RNA polymerase II CTD phosphatase.
   
 0.987
ENSGGOP00000047056
CPSF_A domain-containing protein.
    
 0.976
PCF11
PCF11 cleavage and polyadenylation factor subunit.
    
 0.975
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.