| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC6 | RET | ENSGGOP00000029634 | ENSGGOP00000003517 | Coiled-coil domain containing 6. | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. | 0.959 |
| G3QTT4_GORGO | GDNF | ENSGGOP00000006117 | ENSGGOP00000049478 | Neurturin. | Glial cell derived neurotrophic factor. | 0.568 |
| G3QTT4_GORGO | GFRA1 | ENSGGOP00000006117 | ENSGGOP00000018162 | Neurturin. | GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. | 0.928 |
| G3QTT4_GORGO | GFRA2 | ENSGGOP00000006117 | ENSGGOP00000013397 | Neurturin. | GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. | 0.965 |
| G3QTT4_GORGO | GRB2 | ENSGGOP00000006117 | ENSGGOP00000005990 | Neurturin. | Growth factor receptor bound protein 2. | 0.427 |
| G3QTT4_GORGO | PLCG1 | ENSGGOP00000006117 | ENSGGOP00000007654 | Neurturin. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.559 |
| G3QTT4_GORGO | RET | ENSGGOP00000006117 | ENSGGOP00000003517 | Neurturin. | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. | 0.976 |
| G3QYD4_GORGO | GRB2 | ENSGGOP00000007864 | ENSGGOP00000005990 | KRAS proto-oncogene, GTPase. | Growth factor receptor bound protein 2. | 0.657 |
| G3QYD4_GORGO | HRAS | ENSGGOP00000007864 | ENSGGOP00000039143 | KRAS proto-oncogene, GTPase. | HRas proto-oncogene, GTPase. | 0.997 |
| G3QYD4_GORGO | NRAS | ENSGGOP00000007864 | ENSGGOP00000032900 | KRAS proto-oncogene, GTPase. | NRAS proto-oncogene, GTPase. | 0.997 |
| G3QYD4_GORGO | RET | ENSGGOP00000007864 | ENSGGOP00000003517 | KRAS proto-oncogene, GTPase. | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. | 0.969 |
| GDNF | G3QTT4_GORGO | ENSGGOP00000049478 | ENSGGOP00000006117 | Glial cell derived neurotrophic factor. | Neurturin. | 0.568 |
| GDNF | GFRA1 | ENSGGOP00000049478 | ENSGGOP00000018162 | Glial cell derived neurotrophic factor. | GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. | 0.933 |
| GDNF | GFRA2 | ENSGGOP00000049478 | ENSGGOP00000013397 | Glial cell derived neurotrophic factor. | GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. | 0.738 |
| GDNF | PLCG1 | ENSGGOP00000049478 | ENSGGOP00000007654 | Glial cell derived neurotrophic factor. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.480 |
| GDNF | RET | ENSGGOP00000049478 | ENSGGOP00000003517 | Glial cell derived neurotrophic factor. | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. | 0.969 |
| GFRA1 | G3QTT4_GORGO | ENSGGOP00000018162 | ENSGGOP00000006117 | GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. | Neurturin. | 0.928 |
| GFRA1 | GDNF | ENSGGOP00000018162 | ENSGGOP00000049478 | GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. | Glial cell derived neurotrophic factor. | 0.933 |
| GFRA1 | RET | ENSGGOP00000018162 | ENSGGOP00000003517 | GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. | 0.993 |
| GFRA2 | G3QTT4_GORGO | ENSGGOP00000013397 | ENSGGOP00000006117 | GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. | Neurturin. | 0.965 |
