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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2351 aa)    
Predicted Functional Partners:
G3RKU3_GORGO
Uncharacterized protein.
    
 0.997
F10
Coagulation factor X.
   
 0.941
F9
Coagulation factor IX.
   
 0.937
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.924
F5
Coagulation factor V; Belongs to the multicopper oxidase family.
  
  
0.865
F7
Coagulation factor VII.
   
 0.848
LMAN1
Lectin, mannose binding 1.
    
 0.831
MCFD2
Multiple coagulation factor deficiency 2.
     
 0.831
F11
Coagulation factor XI; Belongs to the peptidase S1 family.
   
 0.769
G3SB50_GORGO
Protein C, inactivator of coagulation factors Va and VIIIa.
    
 0.763
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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