G3QM26_GORGO protein (Gorilla gorilla) - STRING interaction network

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Score

G3QM26_GORGO

Ig-like domain-containing protein. (308 aa)

Predicted Functional Partners:

SIRPA

0.577

CLEC4M

0.547

XDH

0.501

DDX41

0.475

RHAG

0.443

ICOS

0.435

CD209

0.409

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD209	CLEC4M	ENSGGOP00000031836	ENSGGOP00000021876	CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity).	C-type lectin domain family 4 member M; Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates (By similarity).	0.901
CD209	G3QM26_GORGO	ENSGGOP00000031836	ENSGGOP00000003552	CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity).	Ig-like domain-containing protein.	0.409
CLEC4M	CD209	ENSGGOP00000021876	ENSGGOP00000031836	C-type lectin domain family 4 member M; Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates (By similarity).	CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity).	0.901
CLEC4M	G3QM26_GORGO	ENSGGOP00000021876	ENSGGOP00000003552	C-type lectin domain family 4 member M; Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates (By similarity).	Ig-like domain-containing protein.	0.547
DDX41	G3QM26_GORGO	ENSGGOP00000014136	ENSGGOP00000003552	DEAD-box helicase 41.	Ig-like domain-containing protein.	0.475
G3QM26_GORGO	CD209	ENSGGOP00000003552	ENSGGOP00000031836	Ig-like domain-containing protein.	CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity).	0.409
G3QM26_GORGO	CLEC4M	ENSGGOP00000003552	ENSGGOP00000021876	Ig-like domain-containing protein.	C-type lectin domain family 4 member M; Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates (By similarity).	0.547
G3QM26_GORGO	DDX41	ENSGGOP00000003552	ENSGGOP00000014136	Ig-like domain-containing protein.	DEAD-box helicase 41.	0.475
G3QM26_GORGO	ICOS	ENSGGOP00000003552	ENSGGOP00000013753	Ig-like domain-containing protein.	Inducible T cell costimulator.	0.435
G3QM26_GORGO	RHAG	ENSGGOP00000003552	ENSGGOP00000026099	Ig-like domain-containing protein.	Ammonium transporter Rh type A; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.	0.443
G3QM26_GORGO	SIRPA	ENSGGOP00000003552	ENSGGOP00000020934	Ig-like domain-containing protein.	Signal regulatory protein alpha.	0.577
G3QM26_GORGO	XDH	ENSGGOP00000003552	ENSGGOP00000011154	Ig-like domain-containing protein.	Xanthine dehydrogenase.	0.501
ICOS	G3QM26_GORGO	ENSGGOP00000013753	ENSGGOP00000003552	Inducible T cell costimulator.	Ig-like domain-containing protein.	0.435
RHAG	G3QM26_GORGO	ENSGGOP00000026099	ENSGGOP00000003552	Ammonium transporter Rh type A; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.	Ig-like domain-containing protein.	0.443
SIRPA	G3QM26_GORGO	ENSGGOP00000020934	ENSGGOP00000003552	Signal regulatory protein alpha.	Ig-like domain-containing protein.	0.577
XDH	G3QM26_GORGO	ENSGGOP00000011154	ENSGGOP00000003552	Xanthine dehydrogenase.	Ig-like domain-containing protein.	0.501