STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB107ABeta-defensin 107A; Has antibacterial activity; Belongs to the beta-defensin family. (70 aa)    
Predicted Functional Partners:
DEFB1
Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
  
  
 0.905
DEFB106A
Beta-defensin 106A; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2.
  
  
 0.875
DEFB105A
Beta-defensin 105A; Has antimicrobial activity; Belongs to the beta-defensin family.
     
 0.869
DEFB103A
Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family.
     
 0.728
ENSGGOP00000040509
Beta-defensin 103A.
     
 0.728
DEFB110
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.714
DEFB116
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
 0.699
G3QS82_GORGO
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.661
G3QRK3_GORGO
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.645
G3RJR8_GORGO
Uncharacterized protein.
      
 0.605
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.