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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)    
Predicted Functional Partners:
G3R0F2_GORGO
Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.
  
 
0.998
MAPK3
Mitogen-activated protein kinase.
   
0.998
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
0.996
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
0.996
MAPK1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.996
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
   
0.985
MAP3K8
Mitogen-activated protein kinase kinase kinase 8.
  
0.975
LAMTOR3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
    
 0.973
HRAS
HRas proto-oncogene, GTPase.
    
 0.966
NRAS
NRAS proto-oncogene, GTPase.
    
 0.965
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.