NOTCH2 protein (Gorilla gorilla) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Experiments

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[Homology]

Score

NOTCH2

Notch receptor 2. (2373 aa)

Predicted Functional Partners:

DLL4

0.978

RBPJ

0.977

JAG1

0.976

DLL1

0.974

MAML1

0.957

RBPJL

0.940

DLL3

0.940

NOTCH1

0.939

MAML2

0.938

NUMBL

0.930

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLL1	DLL3	ENSGGOP00000005392	ENSGGOP00000047126	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta like canonical Notch ligand 3.	0.930
DLL1	DLL4	ENSGGOP00000005392	ENSGGOP00000028513	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.950
DLL1	JAG1	ENSGGOP00000005392	ENSGGOP00000020660	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.679
DLL1	MAML1	ENSGGOP00000005392	ENSGGOP00000020771	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 1.	0.596
DLL1	MAML2	ENSGGOP00000005392	ENSGGOP00000025466	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 2.	0.594
DLL1	NOTCH1	ENSGGOP00000005392	ENSGGOP00000009720	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.998
DLL1	NOTCH2	ENSGGOP00000005392	ENSGGOP00000003937	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.974
DLL1	NUMBL	ENSGGOP00000005392	ENSGGOP00000019253	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	NUMB like endocytic adaptor protein.	0.420
DLL1	RBPJ	ENSGGOP00000005392	ENSGGOP00000042772	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombination signal binding protein for immunoglobulin kappa J region.	0.827
DLL1	RBPJL	ENSGGOP00000005392	ENSGGOP00000004070	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombination signal binding protein for immunoglobulin kappa J region like.	0.460
DLL3	DLL1	ENSGGOP00000047126	ENSGGOP00000005392	Delta like canonical Notch ligand 3.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.930
DLL3	DLL4	ENSGGOP00000047126	ENSGGOP00000028513	Delta like canonical Notch ligand 3.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.914
DLL3	MAML1	ENSGGOP00000047126	ENSGGOP00000020771	Delta like canonical Notch ligand 3.	Mastermind like transcriptional coactivator 1.	0.525
DLL3	MAML2	ENSGGOP00000047126	ENSGGOP00000025466	Delta like canonical Notch ligand 3.	Mastermind like transcriptional coactivator 2.	0.524
DLL3	NOTCH1	ENSGGOP00000047126	ENSGGOP00000009720	Delta like canonical Notch ligand 3.	Uncharacterized protein.	0.997
DLL3	NOTCH2	ENSGGOP00000047126	ENSGGOP00000003937	Delta like canonical Notch ligand 3.	Notch receptor 2.	0.940
DLL3	RBPJ	ENSGGOP00000047126	ENSGGOP00000042772	Delta like canonical Notch ligand 3.	Recombination signal binding protein for immunoglobulin kappa J region.	0.620
DLL4	DLL1	ENSGGOP00000028513	ENSGGOP00000005392	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.950
DLL4	DLL3	ENSGGOP00000028513	ENSGGOP00000047126	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta like canonical Notch ligand 3.	0.914
DLL4	JAG1	ENSGGOP00000028513	ENSGGOP00000020660	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.535