close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDB1Damage specific DNA binding protein 1. (1147 aa)    
Predicted Functional Partners:
CUL4A
Cullin 4A; Belongs to the cullin family.
   
 0.999
DCAF1
DDB1 and CUL4 associated factor 1.
    
 0.999
G3QLU7_GORGO
RING-type domain-containing protein.
    
 0.999
CUL4B
Cullin 4B; Belongs to the cullin family.
   
 0.999
DDB2
Damage specific DNA binding protein 2.
    
 0.999
CRBN
Cereblon.
    
 0.998
DTL
Denticleless E3 ubiquitin protein ligase homolog.
    
 0.998
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
    
 0.996
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.996
DCAF8
DDB1 and CUL4 associated factor 8.
    
 0.992
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.