STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (471 aa)    
Predicted Functional Partners:
MAML1
Mastermind like transcriptional coactivator 1.
   
 0.985
NOTCH4
Notch receptor 4.
    
 0.961
SNW1
SNW domain containing 1.
    
 0.960
MAML2
Mastermind like transcriptional coactivator 2.
   
 0.960
NOTCH1
Uncharacterized protein.
   
 0.957
CREBBP
CREB binding protein.
    
 0.953
EP300
E1A binding protein p300.
    
 0.949
KAT2A
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
    
 0.948
KAT2B
Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.
    
 0.948
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.946
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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