NCL protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF3A	ENSGGOP00000038934	ENSGGOP00000000035	ENSGGOP00000038934	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	IHABP4_N domain-containing protein.	0.672
EIF3A	FBL	ENSGGOP00000000035	ENSGGOP00000012758	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	Fibrillarin.	0.492
EIF3A	G3R4E0_GORGO	ENSGGOP00000000035	ENSGGOP00000010141	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	SERPINE1 mRNA binding protein 1.	0.672
EIF3A	NCL	ENSGGOP00000000035	ENSGGOP00000004221	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	Nucleolin.	0.887
ENSGGOP00000038934	EIF3A	ENSGGOP00000038934	ENSGGOP00000000035	IHABP4_N domain-containing protein.	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	0.672
ENSGGOP00000038934	ENSGGOP00000049826	ENSGGOP00000038934	ENSGGOP00000049826	IHABP4_N domain-containing protein.	Uncharacterized protein.	0.650
ENSGGOP00000038934	FBL	ENSGGOP00000038934	ENSGGOP00000012758	IHABP4_N domain-containing protein.	Fibrillarin.	0.516
ENSGGOP00000038934	G3S334_GORGO	ENSGGOP00000038934	ENSGGOP00000022484	IHABP4_N domain-containing protein.	Uncharacterized protein.	0.552
ENSGGOP00000038934	G3S9P8_GORGO	ENSGGOP00000038934	ENSGGOP00000024816	IHABP4_N domain-containing protein.	Uncharacterized protein.	0.552
ENSGGOP00000038934	G3SEN9_GORGO	ENSGGOP00000038934	ENSGGOP00000026573	IHABP4_N domain-containing protein.	Nucleoplasmin domain-containing protein.	0.650
ENSGGOP00000038934	HNRNPU	ENSGGOP00000038934	ENSGGOP00000038526	IHABP4_N domain-containing protein.	Heterogeneous nuclear ribonucleoprotein U.	0.664
ENSGGOP00000038934	NCL	ENSGGOP00000038934	ENSGGOP00000004221	IHABP4_N domain-containing protein.	Nucleolin.	0.899
ENSGGOP00000038934	NPM1	ENSGGOP00000038934	ENSGGOP00000037355	IHABP4_N domain-containing protein.	Nucleophosmin 1.	0.650
ENSGGOP00000049826	ENSGGOP00000038934	ENSGGOP00000049826	ENSGGOP00000038934	Uncharacterized protein.	IHABP4_N domain-containing protein.	0.650
ENSGGOP00000049826	FBL	ENSGGOP00000049826	ENSGGOP00000012758	Uncharacterized protein.	Fibrillarin.	0.472
ENSGGOP00000049826	G3R4E0_GORGO	ENSGGOP00000049826	ENSGGOP00000010141	Uncharacterized protein.	SERPINE1 mRNA binding protein 1.	0.650
ENSGGOP00000049826	HNRNPU	ENSGGOP00000049826	ENSGGOP00000038526	Uncharacterized protein.	Heterogeneous nuclear ribonucleoprotein U.	0.720
ENSGGOP00000049826	NCL	ENSGGOP00000049826	ENSGGOP00000004221	Uncharacterized protein.	Nucleolin.	0.926
FBL	EIF3A	ENSGGOP00000012758	ENSGGOP00000000035	Fibrillarin.	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...]	0.492
FBL	ENSGGOP00000038934	ENSGGOP00000012758	ENSGGOP00000038934	Fibrillarin.	IHABP4_N domain-containing protein.	0.516