STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC6Histone deacetylase 6. (1218 aa)    
Predicted Functional Partners:
G3S4Z2_GORGO
Uncharacterized protein.
    
 0.977
VCP
Valosin containing protein; Belongs to the AAA ATPase family.
   
 0.969
TARDBP
RRM domain-containing protein.
   
 0.935
SQSTM1
Sequestosome 1.
   
 
 0.933
EP300
E1A binding protein p300.
    
 0.923
HSP90AB1
Heat shock protein 90 alpha family class B member 1.
    
 0.918
PRKN
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.918
G3RQF7_GORGO
Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
    
 
 0.910
G3RCP0_GORGO
HSF_DOMAIN domain-containing protein.
    
 0.869
RUNX2
Runt domain-containing protein.
   
 0.850
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (38%) [HD]