| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSGGOP00000030528 | SMAD1 | ENSGGOP00000030528 | ENSGGOP00000025615 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.587 |
| ENSGGOP00000030528 | SMAD2 | ENSGGOP00000030528 | ENSGGOP00000004612 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.988 |
| ENSGGOP00000030528 | SMAD3 | ENSGGOP00000030528 | ENSGGOP00000045294 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.981 |
| ENSGGOP00000030528 | SMAD4 | ENSGGOP00000030528 | ENSGGOP00000013332 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.801 |
| ENSGGOP00000030528 | SMAD7 | ENSGGOP00000030528 | ENSGGOP00000010290 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | MH2 domain-containing protein. | 0.901 |
| ENSGGOP00000030528 | SMURF2 | ENSGGOP00000030528 | ENSGGOP00000006862 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | E3 ubiquitin-protein ligase. | 0.753 |
| ENSGGOP00000030528 | TGFBR1 | ENSGGOP00000030528 | ENSGGOP00000051200 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.638 |
| ENSGGOP00000030528 | TGFBR2 | ENSGGOP00000030528 | ENSGGOP00000016505 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.883 |
| ENSGGOP00000030528 | ZFYVE9 | ENSGGOP00000030528 | ENSGGOP00000012377 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Zinc finger FYVE domain-containing protein. | 0.582 |
| FOXH1 | SMAD1 | ENSGGOP00000015870 | ENSGGOP00000025615 | Forkhead box H1. | Mothers against decapentaplegic homolog. | 0.624 |
| FOXH1 | SMAD2 | ENSGGOP00000015870 | ENSGGOP00000004612 | Forkhead box H1. | Mothers against decapentaplegic homolog. | 0.988 |
| FOXH1 | SMAD3 | ENSGGOP00000015870 | ENSGGOP00000045294 | Forkhead box H1. | Mothers against decapentaplegic homolog. | 0.969 |
| FOXH1 | SMAD4 | ENSGGOP00000015870 | ENSGGOP00000013332 | Forkhead box H1. | Mothers against decapentaplegic homolog. | 0.863 |
| SMAD1 | ENSGGOP00000030528 | ENSGGOP00000025615 | ENSGGOP00000030528 | Mothers against decapentaplegic homolog. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.587 |
| SMAD1 | FOXH1 | ENSGGOP00000025615 | ENSGGOP00000015870 | Mothers against decapentaplegic homolog. | Forkhead box H1. | 0.624 |
| SMAD1 | SMAD2 | ENSGGOP00000025615 | ENSGGOP00000004612 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.988 |
| SMAD1 | SMAD3 | ENSGGOP00000025615 | ENSGGOP00000045294 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.977 |
| SMAD1 | SMAD4 | ENSGGOP00000025615 | ENSGGOP00000013332 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD1 | SMAD7 | ENSGGOP00000025615 | ENSGGOP00000010290 | Mothers against decapentaplegic homolog. | MH2 domain-containing protein. | 0.960 |
| SMAD1 | SMURF2 | ENSGGOP00000025615 | ENSGGOP00000006862 | Mothers against decapentaplegic homolog. | E3 ubiquitin-protein ligase. | 0.985 |
