| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARHGEF11 | KMO | ENSGGOP00000026132 | ENSGGOP00000026894 | Rho guanine nucleotide exchange factor 11. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. | 0.409 |
| ARHGEF11 | SH2B3 | ENSGGOP00000026132 | ENSGGOP00000003200 | Rho guanine nucleotide exchange factor 11. | SH2B adaptor protein 3. | 0.571 |
| ARHGEF11 | SHROOM3 | ENSGGOP00000026132 | ENSGGOP00000004807 | Rho guanine nucleotide exchange factor 11. | Shroom family member 3. | 0.568 |
| B3GAT2 | CBR1 | ENSGGOP00000023735 | ENSGGOP00000002907 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. | Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.888 |
| B3GAT2 | DARS2 | ENSGGOP00000023735 | ENSGGOP00000017980 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. | Aspartyl-tRNA synthetase 2, mitochondrial. | 0.746 |
| B3GAT2 | DUSP11 | ENSGGOP00000023735 | ENSGGOP00000009880 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. | Dual specificity phosphatase 11. | 0.872 |
| B3GAT2 | INVS | ENSGGOP00000023735 | ENSGGOP00000017123 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. | Inversin. | 0.894 |
| B3GAT2 | SHROOM3 | ENSGGOP00000023735 | ENSGGOP00000004807 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. | Shroom family member 3. | 0.839 |
| CBR1 | B3GAT2 | ENSGGOP00000002907 | ENSGGOP00000023735 | Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. | 0.888 |
| CBR1 | DARS2 | ENSGGOP00000002907 | ENSGGOP00000017980 | Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Aspartyl-tRNA synthetase 2, mitochondrial. | 0.692 |
| CBR1 | DUSP11 | ENSGGOP00000002907 | ENSGGOP00000009880 | Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Dual specificity phosphatase 11. | 0.832 |
| CBR1 | INVS | ENSGGOP00000002907 | ENSGGOP00000017123 | Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Inversin. | 0.862 |
| CBR1 | SHROOM3 | ENSGGOP00000002907 | ENSGGOP00000004807 | Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Shroom family member 3. | 0.823 |
| DARS2 | B3GAT2 | ENSGGOP00000017980 | ENSGGOP00000023735 | Aspartyl-tRNA synthetase 2, mitochondrial. | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. | 0.746 |
| DARS2 | CBR1 | ENSGGOP00000017980 | ENSGGOP00000002907 | Aspartyl-tRNA synthetase 2, mitochondrial. | Carbonyl reductase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.692 |
| DARS2 | DUSP11 | ENSGGOP00000017980 | ENSGGOP00000009880 | Aspartyl-tRNA synthetase 2, mitochondrial. | Dual specificity phosphatase 11. | 0.666 |
| DARS2 | INVS | ENSGGOP00000017980 | ENSGGOP00000017123 | Aspartyl-tRNA synthetase 2, mitochondrial. | Inversin. | 0.698 |
| DARS2 | SHROOM3 | ENSGGOP00000017980 | ENSGGOP00000004807 | Aspartyl-tRNA synthetase 2, mitochondrial. | Shroom family member 3. | 0.635 |
| DHTKD1 | KMO | ENSGGOP00000040060 | ENSGGOP00000026894 | Dehydrogenase E1 and transketolase domain containing 1. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. | 0.538 |
| DHTKD1 | SHROOM3 | ENSGGOP00000040060 | ENSGGOP00000004807 | Dehydrogenase E1 and transketolase domain containing 1. | Shroom family member 3. | 0.565 |
