IGF1 protein (Gorilla gorilla) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

IGF1

IlGF domain-containing protein. (196 aa)

Predicted Functional Partners:

IGF1R

0.999

INSR

0.999

G3R577_GORGO

0.998

IGFBP4

0.997

IGFBP5

0.996

IGF2

0.984

IGFBP3

0.983

EGF

0.974

DCN

0.972

INS

0.972

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCN	EGF	ENSGGOP00000029810	ENSGGOP00000005698	Decorin; May affect the rate of fibrils formation.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.681
DCN	IGF1	ENSGGOP00000029810	ENSGGOP00000004843	Decorin; May affect the rate of fibrils formation.	IlGF domain-containing protein.	0.972
DCN	IGF1R	ENSGGOP00000029810	ENSGGOP00000012531	Decorin; May affect the rate of fibrils formation.	Tyrosine-protein kinase receptor.	0.534
DCN	IGF2	ENSGGOP00000029810	ENSGGOP00000047744	Decorin; May affect the rate of fibrils formation.	Insulin like growth factor 2.	0.512
DCN	INS	ENSGGOP00000029810	ENSGGOP00000034798	Decorin; May affect the rate of fibrils formation.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.402
EGF	DCN	ENSGGOP00000005698	ENSGGOP00000029810	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Decorin; May affect the rate of fibrils formation.	0.681
EGF	IGF1	ENSGGOP00000005698	ENSGGOP00000004843	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	IlGF domain-containing protein.	0.974
EGF	IGF1R	ENSGGOP00000005698	ENSGGOP00000012531	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.982
EGF	IGF2	ENSGGOP00000005698	ENSGGOP00000047744	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin like growth factor 2.	0.459
EGF	IGFBP5	ENSGGOP00000005698	ENSGGOP00000021127	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin like growth factor binding protein 5.	0.405
EGF	INS	ENSGGOP00000005698	ENSGGOP00000034798	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.979
EGF	INSR	ENSGGOP00000005698	ENSGGOP00000018071	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.963
G3R577_GORGO	IGF1	ENSGGOP00000010446	ENSGGOP00000004843	Insulin like growth factor binding protein 1.	IlGF domain-containing protein.	0.998
G3R577_GORGO	IGF1R	ENSGGOP00000010446	ENSGGOP00000012531	Insulin like growth factor binding protein 1.	Tyrosine-protein kinase receptor.	0.679
G3R577_GORGO	IGF2	ENSGGOP00000010446	ENSGGOP00000047744	Insulin like growth factor binding protein 1.	Insulin like growth factor 2.	0.988
G3R577_GORGO	IGFBP4	ENSGGOP00000010446	ENSGGOP00000009656	Insulin like growth factor binding protein 1.	Insulin like growth factor binding protein 4.	0.929
G3R577_GORGO	INS	ENSGGOP00000010446	ENSGGOP00000034798	Insulin like growth factor binding protein 1.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.672
IGF1	DCN	ENSGGOP00000004843	ENSGGOP00000029810	IlGF domain-containing protein.	Decorin; May affect the rate of fibrils formation.	0.972
IGF1	EGF	ENSGGOP00000004843	ENSGGOP00000005698	IlGF domain-containing protein.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.974
IGF1	G3R577_GORGO	ENSGGOP00000004843	ENSGGOP00000010446	IlGF domain-containing protein.	Insulin like growth factor binding protein 1.	0.998