HEATR5B protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1G1	AP1G2	ENSGGOP00000004709	ENSGGOP00000014434	AP-1 complex subunit gamma.	AP-1 complex subunit gamma.	0.960
AP1G1	AP1M1	ENSGGOP00000004709	ENSGGOP00000004264	AP-1 complex subunit gamma.	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.997
AP1G1	AP1M2	ENSGGOP00000004709	ENSGGOP00000004529	AP-1 complex subunit gamma.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.996
AP1G1	AP1S2	ENSGGOP00000004709	ENSGGOP00000036290	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.995
AP1G1	AP1S2-2	ENSGGOP00000004709	ENSGGOP00000018141	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.927
AP1G1	AP4E1	ENSGGOP00000004709	ENSGGOP00000011323	AP-1 complex subunit gamma.	Adaptor related protein complex 4 subunit epsilon 1.	0.676
AP1G1	AP4M1	ENSGGOP00000004709	ENSGGOP00000040693	AP-1 complex subunit gamma.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.852
AP1G1	G3QZE7_GORGO	ENSGGOP00000004709	ENSGGOP00000008254	AP-1 complex subunit gamma.	Aftiphilin.	0.935
AP1G1	HEATR5B	ENSGGOP00000004709	ENSGGOP00000004914	AP-1 complex subunit gamma.	HEAT repeat containing 5B.	0.664
AP1G2	AP1G1	ENSGGOP00000014434	ENSGGOP00000004709	AP-1 complex subunit gamma.	AP-1 complex subunit gamma.	0.960
AP1G2	AP1M1	ENSGGOP00000014434	ENSGGOP00000004264	AP-1 complex subunit gamma.	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.988
AP1G2	AP1M2	ENSGGOP00000014434	ENSGGOP00000004529	AP-1 complex subunit gamma.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.991
AP1G2	AP1S2	ENSGGOP00000014434	ENSGGOP00000036290	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.997
AP1G2	AP1S2-2	ENSGGOP00000014434	ENSGGOP00000018141	AP-1 complex subunit gamma.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.948
AP1G2	AP4E1	ENSGGOP00000014434	ENSGGOP00000011323	AP-1 complex subunit gamma.	Adaptor related protein complex 4 subunit epsilon 1.	0.667
AP1G2	AP4M1	ENSGGOP00000014434	ENSGGOP00000040693	AP-1 complex subunit gamma.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.852
AP1G2	G3QZE7_GORGO	ENSGGOP00000014434	ENSGGOP00000008254	AP-1 complex subunit gamma.	Aftiphilin.	0.930
AP1G2	HEATR5B	ENSGGOP00000014434	ENSGGOP00000004914	AP-1 complex subunit gamma.	HEAT repeat containing 5B.	0.638
AP1M1	AP1G1	ENSGGOP00000004264	ENSGGOP00000004709	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP-1 complex subunit gamma.	0.997
AP1M1	AP1G2	ENSGGOP00000004264	ENSGGOP00000014434	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	AP-1 complex subunit gamma.	0.988