| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACKR1 | CCL2 | ENSGGOP00000005032 | ENSGGOP00000015811 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | C-C motif chemokine. | 0.844 |
| ACKR1 | CD82 | ENSGGOP00000005032 | ENSGGOP00000041650 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | Tetraspanin. | 0.784 |
| ACKR1 | CXCL1 | ENSGGOP00000005032 | ENSGGOP00000003299 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | C-X-C motif chemokine. | 0.846 |
| ACKR1 | CXCL5 | ENSGGOP00000005032 | ENSGGOP00000028082 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | C-X-C motif chemokine. | 0.695 |
| ACKR1 | G3QXA0_GORGO | ENSGGOP00000005032 | ENSGGOP00000007440 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | SCY domain-containing protein. | 0.835 |
| ACKR1 | KLHL3 | ENSGGOP00000005032 | ENSGGOP00000013848 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | Kelch like family member 3. | 0.678 |
| ACKR1 | NECTIN1 | ENSGGOP00000005032 | ENSGGOP00000035591 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | Uncharacterized protein. | 0.834 |
| ACKR1 | NECTIN2 | ENSGGOP00000005032 | ENSGGOP00000006227 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | Nectin cell adhesion molecule 2. | 0.803 |
| ACKR1 | TNFRSF14 | ENSGGOP00000005032 | ENSGGOP00000042840 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | Uncharacterized protein. | 0.937 |
| ACKR1 | TNFSF14 | ENSGGOP00000005032 | ENSGGOP00000048182 | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | TNF superfamily member 14; Belongs to the tumor necrosis factor family. | 0.672 |
| CCL2 | ACKR1 | ENSGGOP00000015811 | ENSGGOP00000005032 | C-C motif chemokine. | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | 0.844 |
| CCL2 | CXCL1 | ENSGGOP00000015811 | ENSGGOP00000003299 | C-C motif chemokine. | C-X-C motif chemokine. | 0.889 |
| CCL2 | CXCL5 | ENSGGOP00000015811 | ENSGGOP00000028082 | C-C motif chemokine. | C-X-C motif chemokine. | 0.868 |
| CCL2 | G3QXA0_GORGO | ENSGGOP00000015811 | ENSGGOP00000007440 | C-C motif chemokine. | SCY domain-containing protein. | 0.996 |
| CD82 | ACKR1 | ENSGGOP00000041650 | ENSGGOP00000005032 | Tetraspanin. | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | 0.784 |
| CXCL1 | ACKR1 | ENSGGOP00000003299 | ENSGGOP00000005032 | C-X-C motif chemokine. | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | 0.846 |
| CXCL1 | CCL2 | ENSGGOP00000003299 | ENSGGOP00000015811 | C-X-C motif chemokine. | C-C motif chemokine. | 0.889 |
| CXCL1 | CXCL5 | ENSGGOP00000003299 | ENSGGOP00000028082 | C-X-C motif chemokine. | C-X-C motif chemokine. | 0.996 |
| CXCL1 | G3QXA0_GORGO | ENSGGOP00000003299 | ENSGGOP00000007440 | C-X-C motif chemokine. | SCY domain-containing protein. | 0.871 |
| CXCL5 | ACKR1 | ENSGGOP00000028082 | ENSGGOP00000005032 | C-X-C motif chemokine. | Atypical chemokine receptor 1; Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine- binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for [...] | 0.695 |