ACAN protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ACAN

Aggrecan. (2361 aa)

Predicted Functional Partners:

TNR

0.880

TNC

0.821

HAPLN1

0.804

ADAMTS4

0.706

FMOD

0.686

BGN

0.686

G3R317_GORGO

0.681

LUM

0.681

COMP

0.657

TNN

0.626

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAN	ADAMTS4	ENSGGOP00000005155	ENSGGOP00000041572	Aggrecan.	ADAM metallopeptidase with thrombospondin type 1 motif 4.	0.706
ACAN	BGN	ENSGGOP00000005155	ENSGGOP00000034848	Aggrecan.	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.686
ACAN	COMP	ENSGGOP00000005155	ENSGGOP00000007731	Aggrecan.	Cartilage oligomeric matrix protein.	0.657
ACAN	FMOD	ENSGGOP00000005155	ENSGGOP00000011582	Aggrecan.	Fibromodulin.	0.686
ACAN	G3R317_GORGO	ENSGGOP00000005155	ENSGGOP00000009633	Aggrecan.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.681
ACAN	HAPLN1	ENSGGOP00000005155	ENSGGOP00000025195	Aggrecan.	Hyaluronan and proteoglycan link protein 1.	0.804
ACAN	LUM	ENSGGOP00000005155	ENSGGOP00000022526	Aggrecan.	Lumican.	0.681
ACAN	TNC	ENSGGOP00000005155	ENSGGOP00000009901	Aggrecan.	Tenascin C.	0.821
ACAN	TNN	ENSGGOP00000005155	ENSGGOP00000013015	Aggrecan.	Tenascin N.	0.626
ACAN	TNR	ENSGGOP00000005155	ENSGGOP00000015950	Aggrecan.	Tenascin R.	0.880
ADAMTS4	ACAN	ENSGGOP00000041572	ENSGGOP00000005155	ADAM metallopeptidase with thrombospondin type 1 motif 4.	Aggrecan.	0.706
ADAMTS4	BGN	ENSGGOP00000041572	ENSGGOP00000034848	ADAM metallopeptidase with thrombospondin type 1 motif 4.	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.529
ADAMTS4	COMP	ENSGGOP00000041572	ENSGGOP00000007731	ADAM metallopeptidase with thrombospondin type 1 motif 4.	Cartilage oligomeric matrix protein.	0.474
BGN	ACAN	ENSGGOP00000034848	ENSGGOP00000005155	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Aggrecan.	0.686
BGN	ADAMTS4	ENSGGOP00000034848	ENSGGOP00000041572	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	ADAM metallopeptidase with thrombospondin type 1 motif 4.	0.529
BGN	COMP	ENSGGOP00000034848	ENSGGOP00000007731	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Cartilage oligomeric matrix protein.	0.573
BGN	FMOD	ENSGGOP00000034848	ENSGGOP00000011582	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Fibromodulin.	0.907
BGN	LUM	ENSGGOP00000034848	ENSGGOP00000022526	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Lumican.	0.863
COMP	ACAN	ENSGGOP00000007731	ENSGGOP00000005155	Cartilage oligomeric matrix protein.	Aggrecan.	0.657
COMP	ADAMTS4	ENSGGOP00000007731	ENSGGOP00000041572	Cartilage oligomeric matrix protein.	ADAM metallopeptidase with thrombospondin type 1 motif 4.	0.474