HDAC2 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD3	CHD4	ENSGGOP00000013179	ENSGGOP00000018333	Chromodomain helicase DNA binding protein 3.	Uncharacterized protein.	0.999
CHD3	ENSGGOP00000043319	ENSGGOP00000013179	ENSGGOP00000043319	Chromodomain helicase DNA binding protein 3.	WD_REPEATS_REGION domain-containing protein.	0.996
CHD3	GATAD2A	ENSGGOP00000013179	ENSGGOP00000045410	Chromodomain helicase DNA binding protein 3.	GATA zinc finger domain containing 2A.	0.997
CHD3	GATAD2B	ENSGGOP00000013179	ENSGGOP00000036217	Chromodomain helicase DNA binding protein 3.	GATA zinc finger domain containing 2B.	0.996
CHD3	HDAC1	ENSGGOP00000013179	ENSGGOP00000011454	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.997
CHD3	HDAC2	ENSGGOP00000013179	ENSGGOP00000005320	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.996
CHD3	MTA2	ENSGGOP00000013179	ENSGGOP00000013241	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1 family member 2.	0.996
CHD3	MTA3	ENSGGOP00000013179	ENSGGOP00000037680	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1 family member 3.	0.992
CHD3	RCOR1	ENSGGOP00000013179	ENSGGOP00000005215	Chromodomain helicase DNA binding protein 3.	REST corepressor 1.	0.665
CHD3	SIN3A	ENSGGOP00000013179	ENSGGOP00000035548	Chromodomain helicase DNA binding protein 3.	Uncharacterized protein.	0.646
CHD4	CHD3	ENSGGOP00000018333	ENSGGOP00000013179	Uncharacterized protein.	Chromodomain helicase DNA binding protein 3.	0.999
CHD4	ENSGGOP00000043319	ENSGGOP00000018333	ENSGGOP00000043319	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.998
CHD4	GATAD2A	ENSGGOP00000018333	ENSGGOP00000045410	Uncharacterized protein.	GATA zinc finger domain containing 2A.	0.997
CHD4	GATAD2B	ENSGGOP00000018333	ENSGGOP00000036217	Uncharacterized protein.	GATA zinc finger domain containing 2B.	0.997
CHD4	HDAC1	ENSGGOP00000018333	ENSGGOP00000011454	Uncharacterized protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.997
CHD4	HDAC2	ENSGGOP00000018333	ENSGGOP00000005320	Uncharacterized protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.997
CHD4	MTA2	ENSGGOP00000018333	ENSGGOP00000013241	Uncharacterized protein.	Metastasis associated 1 family member 2.	0.998
CHD4	MTA3	ENSGGOP00000018333	ENSGGOP00000037680	Uncharacterized protein.	Metastasis associated 1 family member 3.	0.996
CHD4	RCOR1	ENSGGOP00000018333	ENSGGOP00000005215	Uncharacterized protein.	REST corepressor 1.	0.672
CHD4	SIN3A	ENSGGOP00000018333	ENSGGOP00000035548	Uncharacterized protein.	Uncharacterized protein.	0.717