close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD244CD244 molecule. (365 aa)    
Predicted Functional Partners:
CD48
CD48 molecule.
   
0.999
SH2D1A
SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.
   
 0.995
FYN
Tyrosine-protein kinase.
   
 0.961
G3QN85_GORGO
SLAM family member 6.
   
 0.893
SLAMF8
SLAM family member 8.
   
0.871
SLAMF7
SLAM family member 7.
   
0.819
G3RE11_GORGO
SH2 domain containing 1B.
   
 0.807
NCR1
Natural cytotoxicity triggering receptor 1.
  
  
 0.771
ENSGGOP00000048996
Ig-like domain-containing protein.
   
0.751
CD2
CD2 molecule.
  
 0.747
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
Server load: low (26%) [HD]