MAT1A protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMD1	DNMT1	ENSGGOP00000006324	ENSGGOP00000016186	S-adenosylmethionine decarboxylase proenzyme.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.903
AMD1	DNMT3B	ENSGGOP00000006324	ENSGGOP00000009318	S-adenosylmethionine decarboxylase proenzyme.	DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.900
AMD1	GNMT	ENSGGOP00000006324	ENSGGOP00000013235	S-adenosylmethionine decarboxylase proenzyme.	Glycine N-methyltransferase.	0.928
AMD1	MAT1A	ENSGGOP00000006324	ENSGGOP00000005739	S-adenosylmethionine decarboxylase proenzyme.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.937
AMD1	MAT2A	ENSGGOP00000006324	ENSGGOP00000004838	S-adenosylmethionine decarboxylase proenzyme.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.937
AMD1	MAT2B	ENSGGOP00000006324	ENSGGOP00000024515	S-adenosylmethionine decarboxylase proenzyme.	Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.	0.914
AMD1	MTR	ENSGGOP00000006324	ENSGGOP00000015745	S-adenosylmethionine decarboxylase proenzyme.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.612
BHMT	BHMT2	ENSGGOP00000007397	ENSGGOP00000003155	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	0.996
BHMT	GNMT	ENSGGOP00000007397	ENSGGOP00000013235	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Glycine N-methyltransferase.	0.545
BHMT	MAT1A	ENSGGOP00000007397	ENSGGOP00000005739	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.974
BHMT	MAT2A	ENSGGOP00000007397	ENSGGOP00000004838	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.966
BHMT	MAT2B	ENSGGOP00000007397	ENSGGOP00000024515	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.	0.936
BHMT	MTR	ENSGGOP00000007397	ENSGGOP00000015745	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.945
BHMT	TAT	ENSGGOP00000007397	ENSGGOP00000004601	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.936
BHMT2	BHMT	ENSGGOP00000003155	ENSGGOP00000007397	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.	0.996
BHMT2	GNMT	ENSGGOP00000003155	ENSGGOP00000013235	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Glycine N-methyltransferase.	0.490
BHMT2	MAT1A	ENSGGOP00000003155	ENSGGOP00000005739	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.965
BHMT2	MAT2A	ENSGGOP00000003155	ENSGGOP00000004838	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.966
BHMT2	MAT2B	ENSGGOP00000003155	ENSGGOP00000024515	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.	0.936
BHMT2	MTR	ENSGGOP00000003155	ENSGGOP00000015745	Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.945