STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRSN2Neurensin 2. (204 aa)    
Predicted Functional Partners:
SIRPA
Signal regulatory protein alpha.
      
 0.777
DPP10
Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family.
   
  
 0.765
CNTN4
Contactin 4.
   
  
 0.752
ADCYAP1
Adenylate cyclase activating polypeptide 1.
      
 0.747
TSPAN4
Tetraspanin.
      
 0.634
POLL
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
      
 0.607
G3RRK1_GORGO
Uncharacterized protein.
      
 0.501
SORCS1
Sortilin related VPS10 domain containing receptor 1.
   
  
 0.456
TRIB3
Tribbles pseudokinase 3.
      
 0.417
SNCB
Beta-synuclein; Belongs to the synuclein family.
   
  
 0.409
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.