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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3SK49_GORGOTEA domain transcription factor 4. (453 aa)    
Predicted Functional Partners:
YAP1
Uncharacterized protein.
   
 0.995
G3RQI9_GORGO
WW domain-containing protein.
   
 0.994
WWTR1
WW domain containing transcription regulator 1.
   
 0.959
VGLL4
Vestigial like family member 4.
    
 
 0.940
VGLL1
Vestigial like family member 1.
    
 
 0.901
ENSGGOP00000049090
TEA domain transcription factor 1.
  
 
0.869
FAM181B
Family with sequence similarity 181 member B.
    
   0.849
FAM181A
Family with sequence similarity 181 member A.
    
   0.849
ENSGGOP00000041060
TEA domain transcription factor 2.
  
 
0.842
HOXB13
Homeobox B13.
   
   0.763
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.