USP43 protein (Gorilla gorilla) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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co-expression

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gene neighborhood

gene co-occurrence

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Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3RG63_GORGO	G3RNX2_GORGO	ENSGGOP00000014606	ENSGGOP00000017490	ISG15 ubiquitin like modifier.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.856
G3RG63_GORGO	PCNA	ENSGGOP00000014606	ENSGGOP00000001670	ISG15 ubiquitin like modifier.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.857
G3RG63_GORGO	POLH	ENSGGOP00000014606	ENSGGOP00000041111	ISG15 ubiquitin like modifier.	UmuC domain-containing protein.	0.669
G3RG63_GORGO	RFC1	ENSGGOP00000014606	ENSGGOP00000020543	ISG15 ubiquitin like modifier.	Replication factor C subunit 1.	0.546
G3RG63_GORGO	RFC3	ENSGGOP00000014606	ENSGGOP00000016778	ISG15 ubiquitin like modifier.	Replication factor C subunit 3.	0.555
G3RG63_GORGO	RFC4	ENSGGOP00000014606	ENSGGOP00000031024	ISG15 ubiquitin like modifier.	Replication factor C subunit 4.	0.543
G3RG63_GORGO	UBC	ENSGGOP00000014606	ENSGGOP00000001286	ISG15 ubiquitin like modifier.	Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.489
G3RG63_GORGO	USP43	ENSGGOP00000014606	ENSGGOP00000006281	ISG15 ubiquitin like modifier.	Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family.	0.603
G3RNX2_GORGO	G3RG63_GORGO	ENSGGOP00000017490	ENSGGOP00000014606	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	ISG15 ubiquitin like modifier.	0.856
G3RNX2_GORGO	OTUB1	ENSGGOP00000017490	ENSGGOP00000011815	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	OTU domain-containing protein.	0.484
G3RNX2_GORGO	PCNA	ENSGGOP00000017490	ENSGGOP00000001670	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.907
G3RNX2_GORGO	POLH	ENSGGOP00000017490	ENSGGOP00000041111	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	UmuC domain-containing protein.	0.944
G3RNX2_GORGO	RFC1	ENSGGOP00000017490	ENSGGOP00000020543	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Replication factor C subunit 1.	0.947
G3RNX2_GORGO	RFC3	ENSGGOP00000017490	ENSGGOP00000016778	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Replication factor C subunit 3.	0.980
G3RNX2_GORGO	RFC4	ENSGGOP00000017490	ENSGGOP00000031024	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Replication factor C subunit 4.	0.990
G3RNX2_GORGO	UBC	ENSGGOP00000017490	ENSGGOP00000001286	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.803
G3RNX2_GORGO	USP43	ENSGGOP00000017490	ENSGGOP00000006281	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family.	0.575
OTUB1	G3RNX2_GORGO	ENSGGOP00000011815	ENSGGOP00000017490	OTU domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.484
OTUB1	PCNA	ENSGGOP00000011815	ENSGGOP00000001670	OTU domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.578
OTUB1	UBC	ENSGGOP00000011815	ENSGGOP00000001286	OTU domain-containing protein.	Polyubiquitin-C; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair [...]	0.802