AMD1 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMD1	DNMT1	ENSGGOP00000006324	ENSGGOP00000016186	S-adenosylmethionine decarboxylase proenzyme.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.903
AMD1	DNMT3A	ENSGGOP00000006324	ENSGGOP00000048120	S-adenosylmethionine decarboxylase proenzyme.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.900
AMD1	DNMT3B	ENSGGOP00000006324	ENSGGOP00000009318	S-adenosylmethionine decarboxylase proenzyme.	DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.900
AMD1	G3RTH2_GORGO	ENSGGOP00000006324	ENSGGOP00000019097	S-adenosylmethionine decarboxylase proenzyme.	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family.	0.970
AMD1	GNMT	ENSGGOP00000006324	ENSGGOP00000013235	S-adenosylmethionine decarboxylase proenzyme.	Glycine N-methyltransferase.	0.928
AMD1	MAT1A	ENSGGOP00000006324	ENSGGOP00000005739	S-adenosylmethionine decarboxylase proenzyme.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.937
AMD1	MAT2A	ENSGGOP00000006324	ENSGGOP00000004838	S-adenosylmethionine decarboxylase proenzyme.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.937
AMD1	MAT2B	ENSGGOP00000006324	ENSGGOP00000024515	S-adenosylmethionine decarboxylase proenzyme.	Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.	0.914
AMD1	SMS	ENSGGOP00000006324	ENSGGOP00000003072	S-adenosylmethionine decarboxylase proenzyme.	PABS domain-containing protein.	0.965
AMD1	SRM	ENSGGOP00000006324	ENSGGOP00000014029	S-adenosylmethionine decarboxylase proenzyme.	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family.	0.970
DNMT1	AMD1	ENSGGOP00000016186	ENSGGOP00000006324	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	S-adenosylmethionine decarboxylase proenzyme.	0.903
DNMT1	DNMT3A	ENSGGOP00000016186	ENSGGOP00000048120	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.998
DNMT1	DNMT3B	ENSGGOP00000016186	ENSGGOP00000009318	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.999
DNMT1	GNMT	ENSGGOP00000016186	ENSGGOP00000013235	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Glycine N-methyltransferase.	0.936
DNMT1	MAT1A	ENSGGOP00000016186	ENSGGOP00000005739	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.907
DNMT1	MAT2A	ENSGGOP00000016186	ENSGGOP00000004838	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.911
DNMT1	MAT2B	ENSGGOP00000016186	ENSGGOP00000024515	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.	0.925
DNMT3A	AMD1	ENSGGOP00000048120	ENSGGOP00000006324	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	S-adenosylmethionine decarboxylase proenzyme.	0.900
DNMT3A	DNMT1	ENSGGOP00000048120	ENSGGOP00000016186	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.998
DNMT3A	DNMT3B	ENSGGOP00000048120	ENSGGOP00000009318	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.997