STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (745 aa)    
Predicted Functional Partners:
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
    
 0.999
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
    
 0.999
DLGAP1
DLG associated protein 1.
   
 0.998
ERBB4
Receptor protein-tyrosine kinase.
    
 0.990
DLG3
Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family.
  
 
0.986
GRIN2C
Glutamate ionotropic receptor NMDA type subunit 2C.
    
 0.982
CACNG2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
    
 0.979
LLGL1
LLGL scribble cell polarity complex component 1.
   
 0.974
G3QHC9_GORGO
Glutamate ionotropic receptor NMDA type subunit 1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
   
 0.972
GRIK2
Glutamate ionotropic receptor kainate type subunit 2.
   
 0.972
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.