STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3QW50_GORGOBCR activator of RhoGEF and GTPase. (1101 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.924
ABL1
Tyrosine-protein kinase.
    
 0.895
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
    
   0.678
MYO9A
Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.667
MYO9B
Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.667
KIT
Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.656
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
   
 0.586
G3RWF8_GORGO
MLLT3 super elongation complex subunit.
      
 0.573
RARA
Uncharacterized protein.
      
 0.570
DCAF5
DDB1 and CUL4 associated factor 5.
      
 0.570
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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