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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK2Non-specific serine/threonine protein kinase. (524 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.992
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.991
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.982
PAK1
Non-specific serine/threonine protein kinase.
  
 
0.966
RAC2
Rac family small GTPase 2.
   
 0.966
NCK1
Cytoplasmic protein.
    
 0.962
NCK2
Cytoplasmic protein.
    
 0.962
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 0.958
MYLK
Myosin light chain kinase.
    
0.949
LIMK1
LIM domain kinase 1.
    
0.943
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.