FXN protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CP	FECH	ENSGGOP00000020772	ENSGGOP00000022422	Ceruloplasmin; Belongs to the multicopper oxidase family.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.934
CP	FTH1	ENSGGOP00000020772	ENSGGOP00000016973	Ceruloplasmin; Belongs to the multicopper oxidase family.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.905
CP	FTL	ENSGGOP00000020772	ENSGGOP00000047187	Ceruloplasmin; Belongs to the multicopper oxidase family.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.917
CP	FTMT	ENSGGOP00000020772	ENSGGOP00000001491	Ceruloplasmin; Belongs to the multicopper oxidase family.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.905
CP	FXN	ENSGGOP00000020772	ENSGGOP00000046561	Ceruloplasmin; Belongs to the multicopper oxidase family.	Frataxin.	0.915
CP	G3RT60_GORGO	ENSGGOP00000020772	ENSGGOP00000018985	Ceruloplasmin; Belongs to the multicopper oxidase family.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.905
CP	HEPHL1	ENSGGOP00000020772	ENSGGOP00000025447	Ceruloplasmin; Belongs to the multicopper oxidase family.	Hephaestin like 1; Belongs to the multicopper oxidase family.	0.902
FECH	CP	ENSGGOP00000022422	ENSGGOP00000020772	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.934
FECH	FTH1	ENSGGOP00000022422	ENSGGOP00000016973	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.907
FECH	FTL	ENSGGOP00000022422	ENSGGOP00000047187	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.924
FECH	FTMT	ENSGGOP00000022422	ENSGGOP00000001491	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.940
FECH	FXN	ENSGGOP00000022422	ENSGGOP00000046561	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Frataxin.	0.984
FECH	G3RT60_GORGO	ENSGGOP00000022422	ENSGGOP00000018985	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.906
FECH	HEPHL1	ENSGGOP00000022422	ENSGGOP00000025447	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Hephaestin like 1; Belongs to the multicopper oxidase family.	0.941
FECH	ISCU	ENSGGOP00000022422	ENSGGOP00000011292	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.517
FECH	LYRM4	ENSGGOP00000022422	ENSGGOP00000031177	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	LYR motif containing 4; Belongs to the complex I LYR family.	0.419
FECH	NFS1	ENSGGOP00000022422	ENSGGOP00000024202	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Aminotran_5 domain-containing protein.	0.555
FTH1	CP	ENSGGOP00000016973	ENSGGOP00000020772	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.905
FTH1	FECH	ENSGGOP00000016973	ENSGGOP00000022422	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.907
FTH1	FTL	ENSGGOP00000016973	ENSGGOP00000047187	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.994