STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3QXK1_GORGOZinc finger protein 683. (524 aa)    
Predicted Functional Partners:
CTSG
Granzyme H; Belongs to the peptidase S1 family.
   
  
 0.840
TBX21
T-box transcription factor 21.
   
 
 0.498
CD8A
CD8a molecule.
   
  
 0.496
EOMES
Eomesodermin.
   
 
 0.491
KLRD1
Killer cell lectin like receptor D1.
   
 0.490
G3RB29_GORGO
Granzyme B; Belongs to the peptidase S1 family.
   
  
 0.489
CD69
CD69 molecule.
    
 0.481
ITGAE
Integrin subunit alpha E; Belongs to the integrin alpha chain family.
   
  
 0.454
ITGA1
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
   
  
 0.451
RUNX3
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
   
  
 0.451
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.