close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGB3Integrin beta; Belongs to the integrin beta chain family. (837 aa)    
Predicted Functional Partners:
ITGA2B
Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.
   
 0.999
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 0.999
TLN1
FERM domain-containing protein.
   
 0.993
SRC
Tyrosine-protein kinase.
   
 0.988
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
   
 0.984
VTN
Vitronectin.
    
 0.983
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.983
FLNA
Filamin A.
   
 0.981
SPP1
Secreted phosphoprotein 1.
    
 0.978
THBS1
Thrombospondin 1.
   
 0.977
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.