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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3QY00_GORGOWAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)    
Predicted Functional Partners:
BMP10
Bone morphogenetic protein 10.
   
 
 0.714
FST
Follistatin.
   
  
 0.688
NTSR1
Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.672
FSTL4
Follistatin like 4.
   
  
 0.671
GDF15
Growth differentiation factor 15.
   
 
 0.665
BMP15
Bone morphogenetic protein 15.
   
 
 0.631
FSHR
Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
   
  
 0.623
GDF9
Growth differentiation factor 9.
   
 
 0.618
GDF11
Growth differentiation factor 11.
   
 
 0.586
MSTN
Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.
   
 
 0.546
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.