STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIPCLipase C, hepatic type. (499 aa)    
Predicted Functional Partners:
LIPF
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
   
 
 0.960
APOB
Apolipoprotein B.
   
 0.958
PNPLA2
Patatin like phospholipase domain containing 2.
     
 0.941
PNPLA3
Patatin like phospholipase domain containing 3.
     
 0.940
MGLL
Monoglyceride lipase.
     
 0.920
CEL
COesterase domain-containing protein.
   
 0.919
G3R2A5_GORGO
Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
    
0.915
APOE
Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]
     
 0.912
PNLIP
Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
    
0.911
PLPP4
Uncharacterized protein.
    
 0.909
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.