NR1H4 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB11	FABP6	ENSGGOP00000043567	ENSGGOP00000004547	ATP binding cassette subfamily B member 11.	Fatty acid binding protein 6.	0.627
ABCB11	NR0B2	ENSGGOP00000043567	ENSGGOP00000044190	ATP binding cassette subfamily B member 11.	Nuclear receptor subfamily 0 group B member 2.	0.731
ABCB11	NR1H4	ENSGGOP00000043567	ENSGGOP00000007955	ATP binding cassette subfamily B member 11.	Nuclear receptor subfamily 1 group H member 4.	0.832
ENSGGOP00000038823	G3S6F8_GORGO	ENSGGOP00000038823	ENSGGOP00000023665	Nuclear receptor corepressor 1.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.696
ENSGGOP00000038823	NCOA1	ENSGGOP00000038823	ENSGGOP00000011007	Nuclear receptor corepressor 1.	Nuclear receptor coactivator.	0.713
ENSGGOP00000038823	NCOA2	ENSGGOP00000038823	ENSGGOP00000023853	Nuclear receptor corepressor 1.	Nuclear receptor coactivator.	0.670
ENSGGOP00000038823	NCOA3	ENSGGOP00000038823	ENSGGOP00000019561	Nuclear receptor corepressor 1.	Nuclear receptor coactivator.	0.630
ENSGGOP00000038823	NR0B2	ENSGGOP00000038823	ENSGGOP00000044190	Nuclear receptor corepressor 1.	Nuclear receptor subfamily 0 group B member 2.	0.645
ENSGGOP00000038823	NR1H4	ENSGGOP00000038823	ENSGGOP00000007955	Nuclear receptor corepressor 1.	Nuclear receptor subfamily 1 group H member 4.	0.880
ENSGGOP00000038823	PPARGC1A	ENSGGOP00000038823	ENSGGOP00000009586	Nuclear receptor corepressor 1.	PPARG coactivator 1 alpha.	0.520
ENSGGOP00000038823	RXRA	ENSGGOP00000038823	ENSGGOP00000041308	Nuclear receptor corepressor 1.	Retinoid X receptor alpha.	0.963
FABP6	ABCB11	ENSGGOP00000004547	ENSGGOP00000043567	Fatty acid binding protein 6.	ATP binding cassette subfamily B member 11.	0.627
FABP6	NCOA1	ENSGGOP00000004547	ENSGGOP00000011007	Fatty acid binding protein 6.	Nuclear receptor coactivator.	0.434
FABP6	NCOA2	ENSGGOP00000004547	ENSGGOP00000023853	Fatty acid binding protein 6.	Nuclear receptor coactivator.	0.439
FABP6	NCOA3	ENSGGOP00000004547	ENSGGOP00000019561	Fatty acid binding protein 6.	Nuclear receptor coactivator.	0.467
FABP6	NR0B2	ENSGGOP00000004547	ENSGGOP00000044190	Fatty acid binding protein 6.	Nuclear receptor subfamily 0 group B member 2.	0.638
FABP6	NR1H4	ENSGGOP00000004547	ENSGGOP00000007955	Fatty acid binding protein 6.	Nuclear receptor subfamily 1 group H member 4.	0.838
G3S6F8_GORGO	ENSGGOP00000038823	ENSGGOP00000023665	ENSGGOP00000038823	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 1.	0.696
G3S6F8_GORGO	NCOA1	ENSGGOP00000023665	ENSGGOP00000011007	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.764
G3S6F8_GORGO	NCOA2	ENSGGOP00000023665	ENSGGOP00000023853	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.731