| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FAM13A | HERC4 | ENSGGOP00000018248 | ENSGGOP00000008075 | Family with sequence similarity 13 member A. | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | 0.735 |
| FAM13A | MYPN | ENSGGOP00000018248 | ENSGGOP00000005587 | Family with sequence similarity 13 member A. | Myopalladin. | 0.745 |
| G3RG63_GORGO | HERC4 | ENSGGOP00000014606 | ENSGGOP00000008075 | ISG15 ubiquitin like modifier. | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | 0.777 |
| G3RG63_GORGO | TRIM5 | ENSGGOP00000014606 | ENSGGOP00000022424 | ISG15 ubiquitin like modifier. | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] | 0.463 |
| G3RG63_GORGO | UBE2L6 | ENSGGOP00000014606 | ENSGGOP00000005131 | ISG15 ubiquitin like modifier. | Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. | 0.994 |
| HERC4 | FAM13A | ENSGGOP00000008075 | ENSGGOP00000018248 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | Family with sequence similarity 13 member A. | 0.735 |
| HERC4 | G3RG63_GORGO | ENSGGOP00000008075 | ENSGGOP00000014606 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | ISG15 ubiquitin like modifier. | 0.777 |
| HERC4 | IFT88 | ENSGGOP00000008075 | ENSGGOP00000015131 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | Intraflagellar transport 88. | 0.632 |
| HERC4 | IPO11 | ENSGGOP00000008075 | ENSGGOP00000041763 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | Importin 11. | 0.568 |
| HERC4 | MYPN | ENSGGOP00000008075 | ENSGGOP00000005587 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | Myopalladin. | 0.678 |
| HERC4 | PDE6D | ENSGGOP00000008075 | ENSGGOP00000013177 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...] | 0.741 |
| HERC4 | RPGRIP1 | ENSGGOP00000008075 | ENSGGOP00000010557 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | RPGR interacting protein 1. | 0.616 |
| HERC4 | TRIM5 | ENSGGOP00000008075 | ENSGGOP00000022424 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | Tripartite motif-containing protein 5; Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice. Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1- UBE2N (als [...] | 0.627 |
| HERC4 | UBE2L6 | ENSGGOP00000008075 | ENSGGOP00000005131 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. | 0.595 |
| HERC4 | WHRN | ENSGGOP00000008075 | ENSGGOP00000019513 | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | Whirlin. | 0.592 |
| IFT88 | HERC4 | ENSGGOP00000015131 | ENSGGOP00000008075 | Intraflagellar transport 88. | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | 0.632 |
| IFT88 | PDE6D | ENSGGOP00000015131 | ENSGGOP00000013177 | Intraflagellar transport 88. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...] | 0.676 |
| IFT88 | RPGRIP1 | ENSGGOP00000015131 | ENSGGOP00000010557 | Intraflagellar transport 88. | RPGR interacting protein 1. | 0.788 |
| IFT88 | WHRN | ENSGGOP00000015131 | ENSGGOP00000019513 | Intraflagellar transport 88. | Whirlin. | 0.874 |
| IPO11 | HERC4 | ENSGGOP00000041763 | ENSGGOP00000008075 | Importin 11. | HECT and RLD domain containing E3 ubiquitin protein ligase 4. | 0.568 |
