| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BRCA1 | UBE2E1 | ENSGGOP00000023921 | ENSGGOP00000008200 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.843 |
| BRCA1 | UBE2E2 | ENSGGOP00000023921 | ENSGGOP00000047260 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. | 0.818 |
| BRCA1 | UBE2E3 | ENSGGOP00000023921 | ENSGGOP00000029311 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. | 0.840 |
| ENSGGOP00000032650 | ENSGGOP00000047423 | ENSGGOP00000032650 | ENSGGOP00000047423 | STIP1 homology and U-box containing protein 1. | UBIQUITIN_CONJUGAT_2 domain-containing protein. | 0.543 |
| ENSGGOP00000032650 | UBA1 | ENSGGOP00000032650 | ENSGGOP00000007393 | STIP1 homology and U-box containing protein 1. | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | 0.694 |
| ENSGGOP00000032650 | UBE2E1 | ENSGGOP00000032650 | ENSGGOP00000008200 | STIP1 homology and U-box containing protein 1. | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.865 |
| ENSGGOP00000032650 | UBE2E2 | ENSGGOP00000032650 | ENSGGOP00000047260 | STIP1 homology and U-box containing protein 1. | Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. | 0.647 |
| ENSGGOP00000032650 | UBE2E3 | ENSGGOP00000032650 | ENSGGOP00000029311 | STIP1 homology and U-box containing protein 1. | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. | 0.775 |
| ENSGGOP00000047423 | ENSGGOP00000032650 | ENSGGOP00000047423 | ENSGGOP00000032650 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | STIP1 homology and U-box containing protein 1. | 0.543 |
| ENSGGOP00000047423 | UBA1 | ENSGGOP00000047423 | ENSGGOP00000007393 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | 0.693 |
| ENSGGOP00000047423 | UBE2E1 | ENSGGOP00000047423 | ENSGGOP00000008200 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.849 |
| ENSGGOP00000047423 | UBE2E2 | ENSGGOP00000047423 | ENSGGOP00000047260 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. | 0.849 |
| ENSGGOP00000047423 | UBE2E3 | ENSGGOP00000047423 | ENSGGOP00000029311 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. | 0.849 |
| NEDD4 | UBA1 | ENSGGOP00000033535 | ENSGGOP00000007393 | NEDD4 E3 ubiquitin protein ligase. | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | 0.492 |
| NEDD4 | UBE2E1 | ENSGGOP00000033535 | ENSGGOP00000008200 | NEDD4 E3 ubiquitin protein ligase. | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.933 |
| NEDD4 | UBE2E2 | ENSGGOP00000033535 | ENSGGOP00000047260 | NEDD4 E3 ubiquitin protein ligase. | Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. | 0.643 |
| NEDD4 | UBE2E3 | ENSGGOP00000033535 | ENSGGOP00000029311 | NEDD4 E3 ubiquitin protein ligase. | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. | 0.685 |
| OTUB1 | UBA1 | ENSGGOP00000011815 | ENSGGOP00000007393 | OTU domain-containing protein. | Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | 0.440 |
| OTUB1 | UBE2E1 | ENSGGOP00000011815 | ENSGGOP00000008200 | OTU domain-containing protein. | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.870 |
| OTUB1 | UBE2E2 | ENSGGOP00000011815 | ENSGGOP00000047260 | OTU domain-containing protein. | Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. | 0.700 |
