STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1302 aa)    
Predicted Functional Partners:
VEGFB
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.999
VEGFC
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
   
 0.993
VEGFD
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
   
 0.988
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
0.943
FGF2
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
 0.939
CRKL
Uncharacterized protein.
    
 0.937
PDGFB
Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.
   
 0.933
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.932
PDGFC
Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
 0.932
GRB2
Growth factor receptor bound protein 2.
   
 0.921
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.