STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3R0H8_GORGOTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (160 aa)    
Predicted Functional Partners:
RBP4
Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma.
   
 0.997
ENSGGOP00000047328
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.
  
 
 0.934
APP
Amyloid beta precursor protein.
    
 0.892
GC
GC vitamin D binding protein.
   
  
 0.869
ALB
Albumin.
   
 
 0.858
SERPINA7
Serpin family A member 7; Belongs to the serpin family.
   
 0.806
APCS
Pentaxin.
   
 
 0.759
STRA6
Stimulated by retinoic acid 6.
    
 0.759
KMO
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
  
 
 0.758
AFP
Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.
   
 
 0.754
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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