STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CXCR2C-X-C chemokine receptor type 2; Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2 (By similarity). (360 aa)    
Predicted Functional Partners:
CXCL1
C-X-C motif chemokine.
   
 0.982
CXCL5
C-X-C motif chemokine.
   
 0.982
PPBP
C-X-C motif chemokine.
   
 0.979
CXCL6
C-X-C motif chemokine.
   
 0.977
G3SET6_GORGO
C-X-C motif chemokine.
   
 0.977
CXCL3
C-X-C motif chemokine.
   
 0.970
CXCL8
Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family.
   
 
 0.951
GNAI1
G protein subunit alpha i1.
    
 0.941
ENSGGOP00000043747
Uncharacterized protein.
   
 0.933
CXCL12
C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.
    
 0.927
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.