STRINGSTRING
TYR protein (Gorilla gorilla) - STRING interaction network
"TYR" - Tyrosinase in Gorilla gorilla
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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TYRTyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4- dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6- dihydroxyindole) to indole-5,6 quinone (455 aa)    
Predicted Functional Partners:
TH
Tyrosine hydroxylase (528 aa)
     
 
  0.936
DDC
Dopa decarboxylase (aromatic L-amino acid decarboxylase) (480 aa)
         
  0.925
GOT1
Aspartate aminotransferase; Glutamic-oxaloacetic transaminase 1, soluble (413 aa)
     
 
  0.904
TPO
Thyroid peroxidase (933 aa)
     
 
  0.902
GOT2
Aspartate aminotransferase; Glutamic-oxaloacetic transaminase 2, mitochondrial (430 aa)
     
 
    0.902
TAT
Tyrosine aminotransferase (458 aa)
     
 
  0.900
IL4I1
Amine oxidase; Interleukin 4 induced 1 (589 aa)
         
    0.900
MLANA
melan-A (118 aa)
     
   
  0.893
PAH
Phenylalanine hydroxylase (454 aa)
     
 
  0.854
OCA2
OCA2 melanosomal transmembrane protein; Oculocutaneous albinism II (837 aa)
     
   
  0.830
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Gorilla gorilla, gorilla, western gorilla
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