THRA protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSGGOP00000038823	G3S6F8_GORGO	ENSGGOP00000038823	ENSGGOP00000023665	Nuclear receptor corepressor 1.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.696
ENSGGOP00000038823	NCOA1	ENSGGOP00000038823	ENSGGOP00000011007	Nuclear receptor corepressor 1.	Nuclear receptor coactivator.	0.713
ENSGGOP00000038823	THRA	ENSGGOP00000038823	ENSGGOP00000046906	Nuclear receptor corepressor 1.	Uncharacterized protein.	0.984
ENSGGOP00000038823	THRB	ENSGGOP00000038823	ENSGGOP00000007113	Nuclear receptor corepressor 1.	Uncharacterized protein.	0.984
ENSGGOP00000045882	G3R9L0_GORGO	ENSGGOP00000045882	ENSGGOP00000012094	Actin beta.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	0.503
ENSGGOP00000045882	PIK3CA	ENSGGOP00000045882	ENSGGOP00000009158	Actin beta.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.504
ENSGGOP00000045882	PIK3CB	ENSGGOP00000045882	ENSGGOP00000009368	Actin beta.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.503
ENSGGOP00000045882	THRA	ENSGGOP00000045882	ENSGGOP00000046906	Actin beta.	Uncharacterized protein.	0.909
G3R9L0_GORGO	ENSGGOP00000045882	ENSGGOP00000012094	ENSGGOP00000045882	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Actin beta.	0.503
G3R9L0_GORGO	PIK3CA	ENSGGOP00000012094	ENSGGOP00000009158	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.985
G3R9L0_GORGO	PIK3CB	ENSGGOP00000012094	ENSGGOP00000009368	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.973
G3R9L0_GORGO	PIK3R1	ENSGGOP00000012094	ENSGGOP00000050489	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Phosphoinositide-3-kinase regulatory subunit 1.	0.999
G3R9L0_GORGO	PIK3R3	ENSGGOP00000012094	ENSGGOP00000019086	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.997
G3R9L0_GORGO	THRA	ENSGGOP00000012094	ENSGGOP00000046906	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.911
G3R9L0_GORGO	THRB	ENSGGOP00000012094	ENSGGOP00000007113	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.913
G3S6F8_GORGO	ENSGGOP00000038823	ENSGGOP00000023665	ENSGGOP00000038823	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 1.	0.696
G3S6F8_GORGO	NCOA1	ENSGGOP00000023665	ENSGGOP00000011007	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.764
G3S6F8_GORGO	THRA	ENSGGOP00000023665	ENSGGOP00000046906	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.990
G3S6F8_GORGO	THRB	ENSGGOP00000023665	ENSGGOP00000007113	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.952
NCOA1	ENSGGOP00000038823	ENSGGOP00000011007	ENSGGOP00000038823	Nuclear receptor coactivator.	Nuclear receptor corepressor 1.	0.713