NOTCH1 protein (Gorilla gorilla) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

NOTCH1

Uncharacterized protein. (1606 aa)

Predicted Functional Partners:

JAG1

0.999

MAML1

0.999

DLL4

0.999

RBPJ

0.999

DLL1

0.998

DLL3

0.997

PSEN1

0.990

G3QXA1_GORGO

0.990

MAML2

0.988

ENSGGOP00000049329

0.981

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLL1	DLL3	ENSGGOP00000005392	ENSGGOP00000047126	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta like canonical Notch ligand 3.	0.930
DLL1	DLL4	ENSGGOP00000005392	ENSGGOP00000028513	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.950
DLL1	ENSGGOP00000049329	ENSGGOP00000005392	ENSGGOP00000049329	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.717
DLL1	G3QXA1_GORGO	ENSGGOP00000005392	ENSGGOP00000007441	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.437
DLL1	JAG1	ENSGGOP00000005392	ENSGGOP00000020660	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.679
DLL1	MAML1	ENSGGOP00000005392	ENSGGOP00000020771	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 1.	0.596
DLL1	MAML2	ENSGGOP00000005392	ENSGGOP00000025466	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 2.	0.594
DLL1	NOTCH1	ENSGGOP00000005392	ENSGGOP00000009720	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.998
DLL1	PSEN1	ENSGGOP00000005392	ENSGGOP00000002100	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.516
DLL1	RBPJ	ENSGGOP00000005392	ENSGGOP00000042772	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombination signal binding protein for immunoglobulin kappa J region.	0.827
DLL3	DLL1	ENSGGOP00000047126	ENSGGOP00000005392	Delta like canonical Notch ligand 3.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.930
DLL3	DLL4	ENSGGOP00000047126	ENSGGOP00000028513	Delta like canonical Notch ligand 3.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.914
DLL3	ENSGGOP00000049329	ENSGGOP00000047126	ENSGGOP00000049329	Delta like canonical Notch ligand 3.	Uncharacterized protein.	0.563
DLL3	MAML1	ENSGGOP00000047126	ENSGGOP00000020771	Delta like canonical Notch ligand 3.	Mastermind like transcriptional coactivator 1.	0.525
DLL3	MAML2	ENSGGOP00000047126	ENSGGOP00000025466	Delta like canonical Notch ligand 3.	Mastermind like transcriptional coactivator 2.	0.524
DLL3	NOTCH1	ENSGGOP00000047126	ENSGGOP00000009720	Delta like canonical Notch ligand 3.	Uncharacterized protein.	0.997
DLL3	RBPJ	ENSGGOP00000047126	ENSGGOP00000042772	Delta like canonical Notch ligand 3.	Recombination signal binding protein for immunoglobulin kappa J region.	0.620
DLL4	DLL1	ENSGGOP00000028513	ENSGGOP00000005392	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.950
DLL4	DLL3	ENSGGOP00000028513	ENSGGOP00000047126	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta like canonical Notch ligand 3.	0.914
DLL4	ENSGGOP00000049329	ENSGGOP00000028513	ENSGGOP00000049329	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.693