| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCAR2 | SIRT1 | ENSGGOP00000002387 | ENSGGOP00000009943 | Cell cycle and apoptosis regulator 2. | Sirtuin 1. | 0.999 |
| FOXO1 | FOXO3 | ENSGGOP00000007922 | ENSGGOP00000003457 | Forkhead box O1. | Forkhead box O3. | 0.972 |
| FOXO1 | PPARG | ENSGGOP00000007922 | ENSGGOP00000032598 | Forkhead box O1. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.593 |
| FOXO1 | PPARGC1A | ENSGGOP00000007922 | ENSGGOP00000009586 | Forkhead box O1. | PPARG coactivator 1 alpha. | 0.993 |
| FOXO1 | SIRT1 | ENSGGOP00000007922 | ENSGGOP00000009943 | Forkhead box O1. | Sirtuin 1. | 0.997 |
| FOXO1 | SIRT2 | ENSGGOP00000007922 | ENSGGOP00000002451 | Forkhead box O1. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.886 |
| FOXO1 | SIRT6 | ENSGGOP00000007922 | ENSGGOP00000008641 | Forkhead box O1. | Sirtuin 6. | 0.470 |
| FOXO1 | SIRT7 | ENSGGOP00000007922 | ENSGGOP00000013619 | Forkhead box O1. | Sirtuin 7. | 0.422 |
| FOXO3 | FOXO1 | ENSGGOP00000003457 | ENSGGOP00000007922 | Forkhead box O3. | Forkhead box O1. | 0.972 |
| FOXO3 | PPARG | ENSGGOP00000003457 | ENSGGOP00000032598 | Forkhead box O3. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.543 |
| FOXO3 | PPARGC1A | ENSGGOP00000003457 | ENSGGOP00000009586 | Forkhead box O3. | PPARG coactivator 1 alpha. | 0.818 |
| FOXO3 | SIRT1 | ENSGGOP00000003457 | ENSGGOP00000009943 | Forkhead box O3. | Sirtuin 1. | 0.995 |
| FOXO3 | SIRT2 | ENSGGOP00000003457 | ENSGGOP00000002451 | Forkhead box O3. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.778 |
| FOXO3 | SIRT6 | ENSGGOP00000003457 | ENSGGOP00000008641 | Forkhead box O3. | Sirtuin 6. | 0.525 |
| FOXO3 | SIRT7 | ENSGGOP00000003457 | ENSGGOP00000013619 | Forkhead box O3. | Sirtuin 7. | 0.417 |
| NAMPT | PPARG | ENSGGOP00000042050 | ENSGGOP00000032598 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.401 |
| NAMPT | SIRT1 | ENSGGOP00000042050 | ENSGGOP00000009943 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | Sirtuin 1. | 0.959 |
| NAMPT | SIRT2 | ENSGGOP00000042050 | ENSGGOP00000002451 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.935 |
| NAMPT | SIRT6 | ENSGGOP00000042050 | ENSGGOP00000008641 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | Sirtuin 6. | 0.936 |
| NAMPT | SIRT7 | ENSGGOP00000042050 | ENSGGOP00000013619 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | Sirtuin 7. | 0.922 |
