| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSGGOP00000042231 | HGS | ENSGGOP00000042231 | ENSGGOP00000009137 | VPS37 C-terminal domain-containing protein. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.886 |
| ENSGGOP00000042231 | MVB12A | ENSGGOP00000042231 | ENSGGOP00000026798 | VPS37 C-terminal domain-containing protein. | Multivesicular body subunit 12A. | 0.991 |
| ENSGGOP00000042231 | MVB12B | ENSGGOP00000042231 | ENSGGOP00000015055 | VPS37 C-terminal domain-containing protein. | Multivesicular body subunit 12B. | 0.986 |
| ENSGGOP00000042231 | TSG101 | ENSGGOP00000042231 | ENSGGOP00000010107 | VPS37 C-terminal domain-containing protein. | Tumor susceptibility 101. | 0.993 |
| ENSGGOP00000042231 | UBAP1 | ENSGGOP00000042231 | ENSGGOP00000000662 | VPS37 C-terminal domain-containing protein. | Ubiquitin associated protein 1. | 0.958 |
| ENSGGOP00000042231 | VPS25 | ENSGGOP00000042231 | ENSGGOP00000015646 | VPS37 C-terminal domain-containing protein. | Vacuolar protein sorting 25 homolog. | 0.948 |
| ENSGGOP00000042231 | VPS28 | ENSGGOP00000042231 | ENSGGOP00000015817 | VPS37 C-terminal domain-containing protein. | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. | 0.995 |
| ENSGGOP00000042231 | VPS37A | ENSGGOP00000042231 | ENSGGOP00000011364 | VPS37 C-terminal domain-containing protein. | VPS37A subunit of ESCRT-I. | 0.900 |
| ENSGGOP00000042231 | VPS37B | ENSGGOP00000042231 | ENSGGOP00000004855 | VPS37 C-terminal domain-containing protein. | VPS37B subunit of ESCRT-I. | 0.967 |
| ENSGGOP00000042231 | VPS37C | ENSGGOP00000042231 | ENSGGOP00000016380 | VPS37 C-terminal domain-containing protein. | VPS37C subunit of ESCRT-I. | 0.948 |
| HGS | ENSGGOP00000042231 | ENSGGOP00000009137 | ENSGGOP00000042231 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS37 C-terminal domain-containing protein. | 0.886 |
| HGS | MVB12A | ENSGGOP00000009137 | ENSGGOP00000026798 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Multivesicular body subunit 12A. | 0.836 |
| HGS | MVB12B | ENSGGOP00000009137 | ENSGGOP00000015055 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Multivesicular body subunit 12B. | 0.819 |
| HGS | TSG101 | ENSGGOP00000009137 | ENSGGOP00000010107 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Tumor susceptibility 101. | 0.998 |
| HGS | UBAP1 | ENSGGOP00000009137 | ENSGGOP00000000662 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Ubiquitin associated protein 1. | 0.932 |
| HGS | VPS25 | ENSGGOP00000009137 | ENSGGOP00000015646 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting 25 homolog. | 0.870 |
| HGS | VPS28 | ENSGGOP00000009137 | ENSGGOP00000015817 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. | 0.965 |
| HGS | VPS37A | ENSGGOP00000009137 | ENSGGOP00000011364 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS37A subunit of ESCRT-I. | 0.886 |
| HGS | VPS37B | ENSGGOP00000009137 | ENSGGOP00000004855 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS37B subunit of ESCRT-I. | 0.865 |
| HGS | VPS37C | ENSGGOP00000009137 | ENSGGOP00000016380 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS37C subunit of ESCRT-I. | 0.777 |
