| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADORA2A | TSHB | ENSGGOP00000012399 | ENSGGOP00000010131 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | Thyroid stimulating hormone subunit beta. | 0.923 |
| CGA | FSHR | ENSGGOP00000030475 | ENSGGOP00000014079 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.806 |
| CGA | LHCGR | ENSGGOP00000030475 | ENSGGOP00000008273 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.729 |
| CGA | TSHB | ENSGGOP00000030475 | ENSGGOP00000010131 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Thyroid stimulating hormone subunit beta. | 0.992 |
| CGA | TSHR | ENSGGOP00000030475 | ENSGGOP00000018300 | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.810 |
| CRHR1 | CRHR2 | ENSGGOP00000035368 | ENSGGOP00000024986 | Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. | Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. | 0.945 |
| CRHR1 | TSHB | ENSGGOP00000035368 | ENSGGOP00000010131 | Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. | Thyroid stimulating hormone subunit beta. | 0.924 |
| CRHR2 | CRHR1 | ENSGGOP00000024986 | ENSGGOP00000035368 | Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. | Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. | 0.945 |
| CRHR2 | TSHB | ENSGGOP00000024986 | ENSGGOP00000010131 | Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. | Thyroid stimulating hormone subunit beta. | 0.924 |
| DRD5 | TSHB | ENSGGOP00000007754 | ENSGGOP00000010131 | Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. | Thyroid stimulating hormone subunit beta. | 0.909 |
| FSHR | CGA | ENSGGOP00000014079 | ENSGGOP00000030475 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.806 |
| FSHR | TSHB | ENSGGOP00000014079 | ENSGGOP00000010131 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Thyroid stimulating hormone subunit beta. | 0.979 |
| G3RIH3_GORGO | TSHB | ENSGGOP00000015476 | ENSGGOP00000010131 | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. | Thyroid stimulating hormone subunit beta. | 0.912 |
| LHCGR | CGA | ENSGGOP00000008273 | ENSGGOP00000030475 | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.729 |
| LHCGR | TSHB | ENSGGOP00000008273 | ENSGGOP00000010131 | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | Thyroid stimulating hormone subunit beta. | 0.972 |
| MC2R | TSHB | ENSGGOP00000004579 | ENSGGOP00000010131 | Melanocortin 2 receptor. | Thyroid stimulating hormone subunit beta. | 0.911 |
| TSHB | ADORA2A | ENSGGOP00000010131 | ENSGGOP00000012399 | Thyroid stimulating hormone subunit beta. | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | 0.923 |
| TSHB | CGA | ENSGGOP00000010131 | ENSGGOP00000030475 | Thyroid stimulating hormone subunit beta. | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. | 0.992 |
| TSHB | CRHR1 | ENSGGOP00000010131 | ENSGGOP00000035368 | Thyroid stimulating hormone subunit beta. | Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. | 0.924 |
| TSHB | CRHR2 | ENSGGOP00000010131 | ENSGGOP00000024986 | Thyroid stimulating hormone subunit beta. | Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. | 0.924 |
