| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CTSK | DNPH1 | ENSGGOP00000021819 | ENSGGOP00000011069 | Cathepsin K; Belongs to the peptidase C1 family. | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. | 0.570 |
| CTSK | SERPINB7 | ENSGGOP00000021819 | ENSGGOP00000010263 | Cathepsin K; Belongs to the peptidase C1 family. | Serpin family B member 7; Belongs to the serpin family. | 0.629 |
| DNPH1 | CTSK | ENSGGOP00000011069 | ENSGGOP00000021819 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. | Cathepsin K; Belongs to the peptidase C1 family. | 0.570 |
| DNPH1 | SERPINB7 | ENSGGOP00000011069 | ENSGGOP00000010263 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. | Serpin family B member 7; Belongs to the serpin family. | 0.547 |
| F2 | IL5 | ENSGGOP00000006823 | ENSGGOP00000011293 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. | 0.559 |
| F2 | SERPINB7 | ENSGGOP00000006823 | ENSGGOP00000010263 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serpin family B member 7; Belongs to the serpin family. | 0.607 |
| G3R4J0_GORGO | GPR87 | ENSGGOP00000010195 | ENSGGOP00000032405 | Chromosome 5 open reading frame 46. | G protein-coupled receptor 87; Belongs to the G-protein coupled receptor 1 family. | 0.581 |
| G3R4J0_GORGO | SERPINB7 | ENSGGOP00000010195 | ENSGGOP00000010263 | Chromosome 5 open reading frame 46. | Serpin family B member 7; Belongs to the serpin family. | 0.517 |
| GPR87 | G3R4J0_GORGO | ENSGGOP00000032405 | ENSGGOP00000010195 | G protein-coupled receptor 87; Belongs to the G-protein coupled receptor 1 family. | Chromosome 5 open reading frame 46. | 0.581 |
| GPR87 | SERPINB7 | ENSGGOP00000032405 | ENSGGOP00000010263 | G protein-coupled receptor 87; Belongs to the G-protein coupled receptor 1 family. | Serpin family B member 7; Belongs to the serpin family. | 0.525 |
| IFNG | IL13 | ENSGGOP00000005908 | ENSGGOP00000004605 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin 13. | 0.831 |
| IFNG | IL4 | ENSGGOP00000005908 | ENSGGOP00000005553 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. | 0.872 |
| IFNG | IL5 | ENSGGOP00000005908 | ENSGGOP00000011293 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. | 0.833 |
| IFNG | SERPINB7 | ENSGGOP00000005908 | ENSGGOP00000010263 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Serpin family B member 7; Belongs to the serpin family. | 0.595 |
| IL13 | IFNG | ENSGGOP00000004605 | ENSGGOP00000005908 | Interleukin 13. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.831 |
| IL13 | IL4 | ENSGGOP00000004605 | ENSGGOP00000005553 | Interleukin 13. | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. | 0.912 |
| IL13 | IL5 | ENSGGOP00000004605 | ENSGGOP00000011293 | Interleukin 13. | Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. | 0.913 |
| IL13 | SERPINB7 | ENSGGOP00000004605 | ENSGGOP00000010263 | Interleukin 13. | Serpin family B member 7; Belongs to the serpin family. | 0.568 |
| IL4 | IFNG | ENSGGOP00000005553 | ENSGGOP00000005908 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.872 |
| IL4 | IL13 | ENSGGOP00000005553 | ENSGGOP00000004605 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. | Interleukin 13. | 0.912 |
